Matthias Mann

Matthias Mann's picture
Director, Department of Proteomics and Signal Transduction
Max-Planck Institute of Biochemistry, Martinsried

2017 ESDR Guest Lecture

Lecture Title:
 Advanced Proteomics Technologies and their Application to Biomedicine
Date: Friday 29 September 2017, 14.05-14.35

Introduced by: Nikolaus Romani

Professor Matthias Mann has contributed breakthroughs that have revolutionised proteomics techniques in biomedical laboratories around the world. His contributions include the “peptide sequence tag” approach which allows proteins to be computationally identified by the fragment spectra; nanoelectrospray which allows minute quantities of protein to be tested; and methods for analysing proteins after extracting them from gels.
Since 2005 he has been Director of the Department of Proteomics and Signal Transduction at the Max Planck Institute for Biochemistry in Munich where his group develops and applies methods of mass spectrometry (MS)-based proteomics in a variety of biological areas.
He is also Program Director at the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen where his Clinical Proteomics group conentrates on large scale analysis of human plasma proteomes.

Recent Publications

Kappei, D.; Scheibe, M.; Paszkowski-Rogacz, M.; Bluhm, A.; Gossmann, T. I.; Dietz, S.; Dejung, M.; Herlyn, H.; Buchholz, F.; Mann, M. et al.: Phylointeractomics reconstructs functional evolution of protein binding. Nature Communications (2017)

Aebersold, R.; Mann, M.: Mass-spectrometric exploration of proteome structure and function. Nature 537 (7620), pp. 347 - 355 (2016)

Coscia, F.; Watters, K. M.; Curtis, M.; Eckert, M. A.; Chiang, C. Y.; Tyanova, S.; Montag, A.; Lastra, R. R.; Lengyel, E.; Mann, M.: Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status. Nature Communications (2016)

Wierer, M.; Mann, M.: Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes. Human Molecular Genetics (2016)

Humphrey, S. J.; Azimifar, S. B.; Mann, M.: High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics. NATURE BIOTECHNOLOGY 33 (9), pp. 990 - 995 (2015)